摘要：层状无机材料的弱层间耦合和大面积表面为构建低导热性无机固体材料提供了基本框架.合成具有足够散射和非谐波性的稳定层状材料,从而降低热导率,仍是一项挑战.本文在层状无机FeOCl材料体系中,通过一步氧化还原反应成功获得了一种结构稳定的富含Fe^(2+)的层状材料,实现了表面和界面的同步改性,并实现了超低的热导率.具体而言,系统的X射线吸收精细结构(XAFS)分析和电子能量损失光谱(EELS)分析表明,碱金属原子的层间插层和表面缺陷的引入诱导了大量Fe^(2+)的存在,从而增强了其非谐波性和声子散射.此外,声子态密度(PDOS)分布也提供了确凿的证据,证明了散射概率的提高和声子模式整体的软化.所制得的层状无机材料Fe(III)_(1−n)Fe(II)_(n)O_(1−x)Cl[K^(+)]_(m)不仅结构稳定,而且在298 K时的热导率比原始FeOCl降低了近60%,低至0.29 W m^(−1) K^(−1),这在层状无机材料中是极低的.这项研究为低导热层状材料的设计提供了新的视角.

摘要：肿瘤微环境中的血管生成是肿瘤细胞对放化疗不敏感的主要原因.在本项研究中,我们设计了一种微环境响应型的纳米颗粒,利用ZrMOF的分解产物抑制肿瘤细胞中的PI3K/AKT/mTOR/VEGF通路,从而克服A549R细胞对顺铂的耐药性.我们将顺铂包裹在Zr-MOF中,并在表面修饰BSA,形成了CDDP@Zr-MOF-BSA纳米复合体,该复合体在肿瘤微环境中有良好的响应性,有助于在肿瘤区域蓄积,展现出卓越的血管生成抑制能力,并能明显降低药物的外排.此外,CDDP@Zr-MOFBSA能显著抑制多药耐药相关蛋白1(MRP1)的表达,从而逆转A549R细胞的耐药性.总体而言,CDDP@Zr-MOF-BSA对A549R有细胞毒性,能抑制肿瘤微环境中的血管生成,最终有效提高顺铂耐药肿瘤的治疗效果.CDDP@Zr-MOF-BSA为放化疗治疗耐药肿瘤提供了一种多功能协同的方法.

摘要：Among surgical procedures,suturing is considered ***,in some situations,suturing is not easy or ***,we present proof of concept of a new self-tightening needle-less suture made of a NiTi *** new device is designed to overcome two demanding steps of traditional suturing:needle introduction and manual *** novel suture is composed only of a short NiTi wire that is able to change shape by exploiting a thermoelastic phase *** shape change is achieved by increasing the temperature from that of the operating room(e.g.,20-22℃)to 32℃using warm *** consists of two steps:suture introduction,in which the suture is in an open configuration,and shape recovery(i.e.,closed configuration).The closed configuration is maintained at human body temperature thanks to peculiar pseudoelastic properties of the NiTi ***,thermal and functional characterization verified the simplicity and effectiveness of the proposed device.

摘要：液晶弹性体(LCEs)是一种刺激响应性材料,具有较大且可逆变形的能力,在软致动器、人造肌肉、光子器件和生物医学工程等领域引起了广泛的关注.与具有永久交联网络的传统液晶弹性体不同,具有共价自适应网络的液晶弹性体(CAN-LCEs)可以通过键交换反应引起的网络重排将多畴液晶弹性体编程为单畴液晶弹性体.此外,CAN-LCEs还具有焊接、自修复、回收、再加工或重新编程的能力.本文综述了CAN-LCEs的最新研究成果,详细讨论了基于各种类型的键交换反应的CAN-LCEs及其设计策略.同时,本文还介绍了共价自适应网络给LCEs带来的新功能,包括焊接、自愈、重塑、回收、重新编程等,并探讨了CAN-LCEs在各种领域的应用前景.最后,本文总结了这一新兴研究领域面临的挑战和潜在的未来发展方向.

摘要：本文设计合成了一种Te^(4+)离子掺杂的Cs_(2)InCl_(5)·H_(2)O单晶,该单晶在紫外光激发下发射明亮橙光.未掺杂的Cs_(2)InCl_(5)·H_(2)O单晶几乎没有发光现象,但Te^(4+)掺杂的Cs_(2)InCl_(5)·H_(2)O单晶,发射峰位于660 nm,并伴随着大的Stokes位移和宽的发光半峰宽(180 nm).结合变温荧光光谱以及飞秒瞬态吸收光谱等表征,揭示了其发光机理为自陷激子发光.零维结构中的强电声耦合以及软晶格有利于形成并稳定自陷激子.特别地,由于Te^(4+)离子的最外层电子结构为5s^(2),对温度变化较为灵敏,Te^(4+)离子掺杂的Cs_(2)InCl_(5)·H_(2)O单晶的发光寿命表现出了非常强的温度依赖性,发光寿命从80 K下的6μs缩短至380 K下的19 ns,320 K处的相对灵敏度达到0.062 K^(-1),可以与传统稀土基光学测温材料相媲美.据我们所知,这是首次将铟基金属卤化物钙钛矿单晶应用于光学测温,将为设计合成新型多功能响应的金属卤化物钙钛矿发光材料提供借鉴意义.

摘要：With the huge consumption of traditional fossil energy and the consequent environmental and economic pressure,the development of a new energy that is cheap,green and rich has become an urgent issue for human *** energy is a kind of abundant green renewable energy,and the technology of solar cells that can convert solar energy into electric energy is one of the effective ways to solve the energy and environmental crisis.

摘要：Taking the Gaussian Schell-model beam as a typical example of partially coherent beams, this paper applies the simulated annealing （SA） algorithm to the design of phase plates for shaping partially coherent beams. A flow diagram is presented to illustrate the procedure of phase optimization by the SA algorithm. Numerical examples demonstrate the advantages of the SA algorithm in shaping partially coherent beams. An uniform flat-topped beam profile with maximum reconstruction error RE 〈 1.74% is achieved. A further extension of the approach is discussed.

摘要：Modification of classic fluorophore to possess the emission transitions between aggregation-induced emission(AIE)and intrinsic emission offers reliable approach to the design of ratiometric fluorescent *** this study,a proton acceptor benzimidazole was integrated with BODIPY to form three compounds,BBI-1/2/3,which demonstrated the AIE(~595 nm,I_(agg))in neutral aqueous medium and intrinsic BODIPYemission(~510 nm,I_(int))in acidic *** the three showed the ratiometric pH sensing behavior in a dual excitation/dual emission mode,yet BBI-3 displayed still the dual emission ratiometric pH sensing *** pH-dependent emission ratio I_(int)/I_(agg)of the three were fully reversible,and no interference was observed from normal abundant chemical species in live *** different p K_a(BBI-1,p K_a4.4;BBI-2,p K_a2.7;BBI-3,p K_a3.6)suggested that the substituents on benzimidazole moiety were essential to govern their functioning pH *** ratiometric imaging of BBI-1 in A549 cells provided an effective intracellular pH(pH_i)calibration formula corresponding to emission ratio of I_(int)/I_(agg).Ratiometric pH_iimaging in A549 cells upon small particle exposure confirmed the particle-induced cellular acidification with this *** particle size and the chemical nature of the particle contribute to the observed acidification *** synchronization of lysosome disruption to cellular acidification in A549 cells upon crystalline silica exposure was directly observed for the first time with BBI-1,showing the potential application of BBI-1 in the study of silicosis and other related *** study demonstrated that endowing fluorophore with AIE/intrinsic emission transition could be a promising strategy for ratiometric sensor design.

摘要：用于生产高附加值燃料和化学品的电化学CO_(2)还原反应(CO_(2)RR)为实现全球碳中和提供了一种有前景的方法.近年来,单原子催化剂(SACs)由于金属的最大原子利用率和独特的催化性能受到越来越多的关注.相比之下,除了具有单原子催化剂的上述优点外,双原子位点催化剂(DASCs)还可以通过调节另一种相邻金属从而实现更复杂、可调的原子结构.作为SAC的更深层次的延伸,DASCs可以为CO_(2)RR带来新的机遇,最近引起了人们的浓厚兴趣.本文中,我们重点介绍了DASCs在提升CO_(2)RR性能方面的最新进展.首先,根据双原子活性位点的几何结构和电子配置,对DASCs的分类、合成和证实进行了讨论.之后,根据结合型、异核和同核双原子位点对DASCs在CO_(2)RR中的催化应用进行了分类.特别是通过系统地分析反应途径和原子结构,详细总结了DASCs在CO_(2)RR中的构效关系.最后,提出了未来设计DASCs面临的机遇和挑战,以启发设计具有高结构精度和高CO_(2)RR活性、选择性的DASCs.

摘要：原则上， Phenylboronic 酸能在三不同 conformers 存在(syn， syn；syn，反和反，反) 与不同精力侧面。处于他们的本国的状态，这些混合物比较喜欢精力充沛地赞成的 syn，反符合构造。在分子的建筑群，然而，功能展出 conformational 差异。与 N 施主混合物，在我们报导的这份报纸，一系列合作水晶由基于 syn 包含 synthons 的设计策略准备了， boronic 酸功能的 syn 符合构造。为这个目的，我们与 1,2-diazo 碎片(alprazolam， 1H-tetrazole， acetazolamide 和 benzotriazole ) 采用了混合物，为共结晶的 1,10-phenanthroline 和 2,2-bipyridine 试验。然而，我们的学习证明在 coformer 的 1,2-diazo 碎片的仅仅的存在不与 syn 保证合作水晶的成功的形成， boronic 酸的 syn 符合构造。