摘要：Future climate change is usually projected by coupled earth system models under specific emission sce- narios designed by integrated assessment models （IAMs）, and this offline approach means there is no interaction between the coupled earth system models and the IAMs. This paper introduces a new method to design possible future emission scenarios and corresponding climate change, in which a simple economic and climate damage component is added to the coupled earth system model of Beijing Normal University （BNU-ESM）. With the growth of population and technological expertise and the declining emission-to-output ratio described in the Dynamic Inte- grated Climate-Economy model, the projected carbon emission is 13.7 Gt C, resulting in a 2.4℃ warming by the end of the twenty-first century （2080-2099） compared with 1980-1999. This paper also suggests the importance of the land and ocean carbon cycle in determining the CO2 con- centration in the atmosphere. It is hoped that in the near future the next generation of coupled earth system models that include both the natural system and the social dimension will be developed.

摘要：In order to compare the sensitivity of short-range ensemble forecasts to different land-surface parameters in the South China region,three perturbation experiments related to the land surface model(LSM),initial soil moisture(ISM),and land–atmosphere coupling coefficient(LCC)were designed,and another control experiment driven by the Global Ensemble Forecast System(GEFS)was also *** ensemble members were initiated at 0000 UTC each day,and integrated for 24 h for a total of 40 days from the period 1 April to 10 May 2019 based on the Weather Research and Forecasting *** results showed that the perturbation experiment of the LSM(LSMPE)had the largest ensemble spread,as well as the lowest ensemble-mean root-mean-square error among the three sets of land-surface perturbed experiments,which indicated that it could represent more uncertainty and less *** ensemble spread of the perturbation experiment of the ISM(ISMPE)was generally less than that of LSMPE but greater than that of LCCPE(the perturbation experiment of the LCC).In particular,although the perturbation of the LCC could not produce greater spread,it had an effective influence on the intensity of ***,the ensemble spread of all the land-surface perturbed experiments was smaller than that of GEFSPE(the control experiment).Therefore,in future,land-surface perturbations and atmospheric perturbations should be combined in the design of ensemble forecasting systems to make the model represent more uncertainties.

摘要：The emerging plant synthetic metabolic engineering has been exhibiting great promise to produce either value-added metabolitesor therapeutic proteins. However, promoters for plant pathway engineering are generally selected empirically. The quantitativecharacterization of plant-based promoters is essential for optimal control of gene expression in plant chassis. Here, we used *** leaves and BY2 suspension cells to quantitatively characterize a library of plant promoters by transient expressionof firefly/Renilla luciferase. We validated the dual-luciferase reporter system by examining the correlation between reporterprotein and mRNA levels. In addition, we investigated the effects of terminator–promoter combinations on gene expressionand found that the combinations of promoters and terminators resulted in a 326-fold difference between the strongest andweakest performance, as reflected in reporter gene expression. As a proof of concept, we used the quantitatively characterizedpromoters to engineer the betalain pathway in N. benthamiana. Seven selected plant promoters with different expressionstrengths were used orthogonally to express CYP76AD1 and DODA, resulting in a final betalain production range of 6.0–362.4 μg/g fresh weight. Our systematic approach not only demonstrates the various intensities of multiple promoter sequencesin N. benthamiana and BY2 cells but also adds to the toolbox of plant promoters for plant engineering.

摘要：This paper presents a case study on structure design and establishment of database application system for alien species in Shandong Province, integrating with Geographic Information System, computer network, and database technology to the research of alien species. The modules of alien species database, including classified data input, statistics and analysis, species pictures and distribution maps, and out date input, were approached by Visual *** 2003 and Microsoft SQL server 2000. The alien species information contains the information of classification, species distinction characteristics, biological characteristics, original area, distribution area, the entering fashion and route, invasion time, invasion reason, interaction with the endemic species, growth state, danger state and spatial information, i.e. distribution map. Based on the above bases, several models including application, checking, modifying, printing, adding and returning models were developed. Furthermore, through the establishment of index tables and index maps, we can also spatially query the data like picture, text and GIS map data. This research established the technological platform of sharing information about scientific resource of alien species in Shandong Province, offering the basis for the dynamic inquiry of alien species, the warning technology of prevention and the fast reaction system. The database application system possessed the principles of good practicability, friendly user interface and convenient usage. It can supply full and accurate information inquiry services of alien species for the users and provide functions of dynamically managing the database for the administrator.

摘要：Phloretin is an important skin-lightening and depigmenting agent from the peel of apples. Although de novo production of phloretin has been realized in microbes using the natural pathway from plants, the efficiency of phloretin production is still not enough for industrial application. Here, we established an artificial pathway in the yeast to produce phloretin via assembling two genes of p-coumaroyl-CoA ligase(4CL) and chalcone synthase(CHS). CHS is a key enzyme which conventionally condenses a CoA-tethered starter with three molecules of malonyl-CoA to form the backbone of flavonoids. However, there was 33% of byproduct generated via CHS by condensing two molecules of malonyl-CoA during the fermentation process. Hence, we introduced a more efficient CHS and improved the supply of malonyl-CoA through two pathways;the by-product ratio was decreased from 33% to 17% and the production of phloretin was improved from 48 to 83.2 mg L^(-1). Finally, a fed-batch fermentation process was optimized and the production of phloretin reached 619.5 mg L^(-1), which was 14-fold higher than that of the previous studies. Our work established a platform for the biosynthesis of phloretin from the low-cost raw material 3-(4-hydroxyphenyl) propanoic acid and also illustrated the potential for industrial scale bio-manufacturing of phloretin.

摘要：Hydrologiska Byrans Vattenbalansavdeling(HBV) Light model was used to evaluate the performance of the model in response to climate change in the snowy and glaciated catchment area of Hunza River Basin. The study aimed to understand the temporal variation of streamflow of Hunza River and its contribution to Indus River System(IRS). HBV model performed fairly well both during calibration(R2=0.87, Reff=0.85, PBIAS=-0.36) and validation(R2=0.86, Reff=0.83, PBIAS=-13.58) periods on daily time scale in the Hunza River Basin. Model performed better on monthly time scale with slightly underestimated low flows period during bothcalibration(R2=0.94, Reff=0.88, PBIAS=0.47) and validation(R2=0.92, Reff=0.85, PBIAS=15.83) periods. Simulated streamflow analysis from 1995-2010 unveiled that the average percentage contribution of snow, rain and glacier melt to the streamflow of Hunza River is about 16.5%, 19.4% and 64% respectively. In addition, the HBV-Light model performance was also evaluated for prediction of future streamflow in the Hunza River using future projected data of three General Circulation Model(GCMs) i.e. BCC-CSM1.1, CanESM2, and MIROCESM under RCP2.6, 4.5 and 8.5 and predictions were made over three time periods, 2010-2039, 2040-2069 and 2070-2099, using 1980-2010 as the control period. Overall projected climate results reveal that temperature and precipitation are the most sensitiveparameters to the streamflow of Hunza River. MIROC-ESM predicted the highest increase in the future streamflow of the Hunza River due to increase in temperature and precipitation under RCP4.5 and 8.5 scenarios from 2010-2099 while predicted slight increase in the streamflow under RCP2.6 during the start and end of the 21 th century. However, BCCCSM1.1 predicted decrease in the streamflow under RCP8.5 due to decrease in temperature and precipitation from 2010-2099. However, Can ESM2 predicted 22%-88% increase in the streamflow under RCP4.5 from 2010-2099. The results of this study could

摘要：A synchrotron-based proton therapy(PT)facility that conforms with the requirement of future development trend in compact PT can be operated without an energy selection *** article demonstrates a novel radiation shielding design for this *** FLUKAbased Monte Carlo simulations have been performed to validate its *** this design,two different shielding scenarios(3-m-thick concrete and 2-m-thick iron–concrete)are proved able to reduce the public annual dose to the limit of 0.1 mSv/*** calculation result shows that the non-primary radiation from a PT system without an inner shielding wall complies with the IEC 60601-2-64 international standard,making a single room a ***,the H/D value of this design decreases from 2.14 to 0.32 mSv/Gy when the distance ranges from 50 to 150 cm from the isocenter,which is consistent with the previous result from another *** establishing a typical time schedule and procedures in a treatment day for a single room in the simulation,a non-urgent machine maintenance time of 10 min after treatment is recommended,and the residual radiation level in most areas can be reduced to 2.5 lSv/*** annual dose for radiation therapists coming from the residual radiation is 1 mSv,which is 20%of the target *** general,this shielding design ensures a low cost and compact facility compared with the cyclotron-based PT system.

摘要：本文系统而扼要地论述了在自然资源保护和经济持续发展中,生态学方面的先决条件。人类活动造成了环境的日益恶化,并威胁着生物圈。第三世界国家必须发展经济,否则,贫穷、饥饿和疾病将危及整个民族的生存,现行的环境持续发展的概念也许只是掩饰矛盾而并不现实。因此必须用新的战略决策使经济增长居于稳定的生态环境之中。如果把生态学原理、方法和现有的知识有效地贯彻到经济计划中,经济的持续发展就会变成现实。发展中国家试图取得经济的持续发展,必须注意以下10个必要生态条件:1.信息的传播。信息传播包括环境科学专业化训练、公众环境知识教育及有关发展计划和决策的生态学概念的诸多内容。应让决策者了解生态学理论基础;2.讲习生态系统知识。制定经济发展计划时必须认清生态系统内部、生态系统之间的相互作用,建立生态系统的概念模型以说明生态系统各组分之间的相互依赖关系;3.必须认识到生态、经济、政治和社会系统间的相互联系,人类及其社会系统是关键所在;4.设计生态系统的经济模型,为决策者提供自然资源的有关信息;5.使自然资源从消耗性利用向非消耗性利用转变;6.加强和下放权力,强制执行环境政策和法规;7.简化有关环境法规,开明地应用环境评价方法。政策与法规不应当超出政府的能力范围,并考虑?

摘要：Photocatalysis is believed to be one of the best methods to realize sustainable H2 production. However, achieving this through heterogeneous photocatalysis still remains a great challenge owing to the absence of active sites, sluggish surface reaction kinetics, insufficient charge separation, and a high thermodynamic barrier. Therefore, cocatalysts are necessary and of great significance in boosting photocatalytic H2 generation. This review will focus on the promising and appealing low-cost Ni-based H2-generation cocatalysts as the alternatives for the high-cost and low-abundance noble metal cocatalysts. Special emphasis has been placed on the design principle, modification strategies for further enhancing the activity and stability of Ni-based cocatalysts, and identification of the exact active sites and surface reaction mechanisms. Particularly, four types of modification strategies based on increased light harvesting, enhanced charge separation, strengthened interface interaction, and improved electrocatalytic activity have been thoroughly discussed and compared in detail. This review may open a new avenue for designing highly active and durable Ni-based cocatalysts for photocatalytic H2 generation.

摘要：Biodiversity assessment for tree species was conducted in three forest fragments ofthe Taita Hills, southeastern Kenya to compare species diversity between and within three exotic forest plantations of pine, eucalyptus, cypress and the indigenous forests. The study sites were： Ngangao （120 ha）, Chawia （86 ha）, and Mbololo （185 ha）. A Y-plot design was used to sample 32 plots comprising of 65 subplots. At each subplot, all juvenile trees of 5 cm and above in diameter at breast height （DBH） were enumerated and recorded by species. Tree regeneration （seedlings and saplings） was tallied by species. The Shannon-Weiner Index was used to calculate species diversity and evenness. The derived Shannon’s indices were further converted into effective numbers to show the magnitude of differences in species biodiversities. To evaluate dif-ferences in species diversities, a one way ANOVA was conducted and to separate the means, Tukey＇s HSD and Duncan’s tests were used for even and uneven number of samples respectively. Jaccard’s similarity index was used to assess species similarities. There were more than 58 species whose stem densities varied between 10 and 2 000 trees per *** were significant differences in species diversities between forest types and sites; the indigenous forests showed higher diversities than the exotic forests. Similarly, Chawia sites had higher species diversity than both Ngangao and Mbololo. Chawia also had a higher number of regen-erated species than the two other sites, including species such as Xymalos monospora, Rapanea melanophloeos, and Syzygium guineense, which are associated with low levels of disturbance. These findings indicate that the indigenous forest is more diverse in species as would be expected in the tropics. The high species diversity in Chawia could be accounted for by the higher levels of disturbance it underwent, unlike the two other sites. The regeneration of species associated with low levels of disturbance found in the ex