摘要：Tissue engineering(TE)continues to be widely explored as a potential solution to meet critical clinical needs for diseased tissue replacement and tissue *** this study,we developed a poly(2-hydroxyethyl methacrylate-co-methacrylic acid)(pHEMA-co-MAA)based hydrogel loaded with newly synthesized conductive poly(3,4-ethylene-dioxythiophene)(PEDOT)and polypyrrole(PPy)nanoparticles(NPs),and subsequently processed these hydrogels into tissue engineered constructs via three-dimensional(3D)*** presence of the NPs was critical as they altered the rheological properties during ***,all samples exhibited suitable shear thinning properties,allowing for the development of an optimized processing window for 3D *** were 3D printed into pre-determined disk-shaped configurations of 2 and 10 mm in height and diameter,*** observed that the NPs disrupted the gel crosslinking efficiencies,leading to shorter degradation times and compressive mechanical properties ranging between 450 and 550 *** conductivity of the printed hydrogels increased along with the NP concentration to(5.10±0.37)×10^(−7)S/*** vitro studies with cortical astrocyte cell cultures demonstrated that exposure to the pHEMA-co-MAA NP hydrogels yielded high cellular viability and proliferation ***,hydrogel antimicrobial studies with staphylococcus epidermidis bacteria revealed that the developed hydrogels affected bacterial *** together,these materials show promise for various TE strategies.

摘要：目的　设计并合成与环佐辛有类似的阿片受体亲和活性、在体内具有较长作用时间的 3 四氢呋喃甲基苯并吗吩烷类似物。方法　 8 三氟甲磺酸酯 3 四氢呋喃甲基苯并吗吩烷经催化氨化制得目标物 ,对目标物进行受体亲和力测定。结果　 8 氨基及 8 苯氨基化合物在体外与 μ ,δ和κ受体的亲和力均较相应的 8 羟基化合物低。 结论　目标化合物的体外受体亲和力相对较低 ,但此结果尚不能完全说明其在体内的作用情况及其可否用于毒品成瘾的治疗。

摘要：Sensitivity analysis is used to quantify the contribution of the uncertainty of input variables to the uncertainty of systematic output *** tolerance design in manufacturing and assembly,sensitivity analysis is applied to help designers allocate tolerances ***,different sensitivity indices derived from different sensitivity analysis methods will always lead to conflicting *** is necessary to find a sensitivity index suitable for tolerance allocation to transmission mechanisms so that the sensitivity results can truly reflect the effects of tolerances on kinematic and dynamic *** this paper,a variety of sensitivity indices are investigated and compared based on hybrid ***,the hybrid simulation model of the crank-slider mechanism is ***,samples of the kinematic and dynamic responses of the mechanism with joint clearances and link length errors are obtained,and the surrogate model established using polynomial chaos expansion(PCE).Then,different sensitivity indices are calculated based on the PCE model and are further used to evaluate the effect of joint clearances and link length errors on the output *** with the tolerance-cost function,the corresponding tolerance allocation schemes are obtained based on different sensitivity analysis ***,the kinematic and dynamic responses of the mechanism adopting different tolerance allocation schemes are simulated,and the sensitivity index corresponding to the optimal response is determined as the most appropriate index.

摘要：数字花布织机的织物把它的设计概念和方法，它在凭手画的模式能表示的以外远启用了是的花布织机的织物设计的创造直接从计算机图象和颜色模式借了。在这份报纸，数字花布织机的织物设计的原则被分类进二部分：无色模式和丰富多彩的模式，和一个创新分层的联合设计方法被建议了与这个新设计概念，数字花布织机的织物能被从无色单个层的结构设计到丰富多彩的复合结构满足。作为结果，设计了无色、丰富多彩的花布织机的织物能够在织物的脸上与一个大水平颜色数字表示如画、相片现实主义的效果。学习的结果具有不能模仿的数字效果和这创造提出的新花布织机的织物 ith 的创造的巨大的利益，这被想象在大量生产的没有问题。

摘要：Modal analysis and seismic response analysis were carried out for the equatorial diagnostic port plug of international thermonuclear experimental reactor (ITER). The aim of the theoretical analysis is to verify structural strength and reliability of the device. The working condition includes one-dimensional seismic wave and two-dimensional seismic wave. Modal analysis of the device shows that primary vibration is inclined to occur in low-order modes. The horizontal (X-direction, Y-direction) maximum vibration appears at the first and the fourth eigen modes, with the natural frequency of 70.59 and 215.88 Hz respectively, and the vertical (Z-direction) primary vibration appears at the second eigen mode with the natural frequency of 82.85 Hz. According to the results of the finite element analysis (FEA) program, the weak portions of the device are distributed in the joint of port body with blanket shielding module (BSM) and inner side wall of ribbed plate for lifting flange, the maximum von Mises stress is 14.8 MPa with the Y-direction seismic wave. In accordance with the design criteria, the destructive effect is far below the failure boundary, and the structural reliability of the equatorial diagnostic port plug can meet the requirements of the design specifications.

摘要：Pattern design and technology play a very important role in the garment industry. In order to improve the level of pattern making and design of the garment industry, a survey was conducted to investigate the industrial needs in pattern design and technology in China's Mainland. The data were collected from the employers and employees from the garment industry and students in the major of fashion and clothing studies. It indicated that there was a gap between the employer and employee, especially the requirements of the industrial needs and the course contents covered by the tertiary schools. The employers expected to recruit more experienced pattern designers, at the same time, they were not reluctant to hire fresh graduates and spent more resources on the training of employees. The students knew little about their employment situation of the garment industry, spent too little time on the course study and learned too little practical skills in pattern design. They could not make use of the knowledge which prevented them from being employed by the garment industry. Efforts should be taken by both the tertiary schools and the garment industry. The students should be aspirated towards the profession of pattern cutters and the syllabuses of pattern making should be more practical and industrial orientated. The solution might benefit the garment industry a lot in a long run.

摘要：Under the constantly changing production and marketing conditions including globalization,the fashion apparel industries are frequently restructuring to maintain customers and sustain *** of the methodologies adopted by manufacturers includes mass customization,which attempts to produce near custom made product at near mass production *** swimwear requires tighter fit tolerance and still has fashion content,it has been used in this study to illustrate the ease of design change,design modification,and ***-style design of swimsuit is very demanding and time-consuming if traditional design methods are *** manufacturers require systems with the capacity to deal with garment design process as a whole,including possibilities to work directly within a 3D graphic ***,it is realised that one of the major challenges in garment design concerns the physically-based simulation of production and 3D *** innovation method consisting of a computer-aided design(CAD)system,allowing the designer to perform multi-style swimsuit design on a customized virtual human body,is presented in this *** 3D visualization and personalization of the simulation results are presented to help the designers to preview and determine whether the design of the swimsuit is satisfactory and then obtain feedback to improve their designs *** new functions of the virtual system provide the abilities to perform intelligent design of various swimsuit styles and materials for different body parts according to individual design *** advantages of innovative design method for swimsuit have been discussed in this paper and examples have been provided to illustrate the ease of use CAD in design simulation and innovation.

摘要：To protect mining areas from electrical fire,it is very important to install electrical fire monitoring system to ensure safety in development of mineral resources and for *** this paper,design for electrical fire monitoring and detection system with optional sensor modules has been *** addition,necessity and suitability of electrical fire monitoring and detection system with optional sensor modules in mining areas have been *** designed electrical fire monitoring and detection system suitable for work environment of mining industry is composed by host-computer monitoring software and slave-computer *** detectors are manufactured by using embedded *** shells deployed have superior enclosure performances and explosion-proof *** is easy to install and maintain the *** general,the system has reached,or even exceeded standards specified in national standards for performances and appearances of such *** results show application of electrical fire monitoring and detection system can effectively enhance monitoring intensity over the mining areas and provide reliable guarantee to ensure orderly development of mineral resources and to protect physical and property safety of citizens in these areas.

摘要：The need for reducing the wear in mechanical parts used in the industry makes self-lubricant films one of the sustainable solutions to achieve long-term protection under different environmental *** purpose of this work is to study the influence of C additions on the tribological behavior of a magnetron-sputtered TiN film in air,water,and *** results show that the addition of C into the TiN binary film induced a new amorphous phase,and the films exhibited a dual phase of fcc(face-centered cubic)-TiN and amorphous *** antifriction and wear-resistance properties were enhanced in air and water by adding 19.1at%***,a further increase in the C concentration improved anti-frictional properties but also led to higher wear *** the amorphous phase induced microbatteries and accelerated the corrosion of TiN phases in seawater,the negative abrasion state was detected for all Ti-C-N films due to the adhesion of the tribocorrosion debris on the wear track.

摘要：Digital woven textiles are one of the latest research areas of digital textiles. The key of research on design of digital woven fabrics lies in structural design. Nowadays, the application of digital design technology has fundamentally changed the concept of structural design of woven fabric, giving rise to design methods and effects that were deemed impossible before. A study has been carried out to analyze the nature of woven structures and the methods of structural design. This paper proposes an innovative principle and method of structural design under digital design concept, on which the design of digital gamut weaves and establishment of weave-database were presented to meet the requirement of balanced interlacement. It is envisaged that the results of this study will enhance future research in creation of digital woven fabrics, with particular emphasis on digital jacquard fabrics. Meanwhile, this study is also laid the foundation for the intelligent design of woven textile.