摘要：Sweat,as a biofluid with the potential for noninvasive collection,provides profound insights into human health conditions,because it contains various chemicals and information to be utilized for the monitoring of well-being,stress levels,exercise,and ***,wearable sweat sensors have been developed as a promising substitute to conventional laboratory sweat detection *** sensors are promising to realize low-cost,real-time,in situ sweat measurements,and provide great opportunities for health status evaluation analysis based on personalized big *** review first presents an overview of wearable sweat sensors from the perspective of basic components,including materials and structures for specific sensing applications and *** strategies and specific methods of the fabrication of wearable power management are also ***,current challenges and future directions of wearable sweat sensors are discussed.

摘要：There are many design parameters to determine a performance of a robot. Especially, in the case of the mobile robots, they requirc complicated motion at various environments to get high performances. In this sense, the analysis of the design parameters is the most important work to design an efficient mobile robot. In this study, we analyze the design parameters for the water-running robot. From the parametric study, we find some solutions to improve the performances of the robot. We derive dynamic equations for the water-running motion, and do a sensitivity analysis to understand the relationships between the parameters （frequency of the leg, stiffness of torsional springs that connects multi frames and mass of frames） and the performance of the water-running motion such as running speed and pitching stability. We use an orthogonal array to make various combinations of the parameters, and to reduce the number of a simulation process. As results, we summarize some solutions to improve the water-running motion. We are expecting that this study is going to be used to design robots that are operated on the water.

摘要：A new type of V-shaped photonic crystal fiber with elliptical air-holes is proposed to realize simultaneous high bire- fringence and nonlinearity at a wavelength of 1.55 μm. The full vector finite element method was adopted to investigate its characteristics, including birefringence, nonlinearity, and dispersion. The PCF exhibited a very high birefringence of 2.89x10-2 and very high nonlinear coefficient of 102.69 W-1 .km 1. In particular, there were two zero-dispersion wave- lengths （ZDWs） in the visible （X： 640-720 nm and Y： 730-760 nm） and near-infrared regions （X： 1050-1606 nm and Y： 850-1500 nm）. The combination of high birefringence and nonlinearity allowed the PCF to maintain the polarization state and generate a broadband super continuum, with potential applications in nonlinear optics.

摘要：In this paper, a novel approach is proposed for solving the parameter design problem of brushless direct current(BLDC) motor, which is based on the membrane computing(MC) and pigeon-inspired optimization(PIO) algorithm. The motor parameter design problem is converted to an optimization problem with five design parameters and six constraints. The PIO algorithm is introduced into the framework of MC for improving the global convergence performance. The hybrid algorithm can improve the population diversity with better searching efficiency. Comparative simulations are conducted, and comparative results are given to show the feasibility and effectiveness of our proposed hybrid algorithm for high nonlinear optimization problems.

摘要：A methodology drugs based on traditional to develop multi-component Chinese medicines has been developed using central composite design. Several active components from the traditional Chinese medicine turmeric were chosen for use in a multi-component antitumor drug. Response surface methodology based on a central composite design was applied to determine the quantitative composition-activity relationships in order to optimize the amount of each component in the drug. An MTT （3-（4,5- dimethylthiazol-2-yl）-2,5-diphenyltetrazolium bromide） assay was used to measure the pharmacological activity as the response value. The experimental antitumor activity of the optimum combination was 92.85% in the MTT assay and superior to the activities of each single component. These results demonstrate that response surface methodology based on a central composite design is suitable for the design of multi-component drugs.

摘要：Cell migration is facilitated by the interaction of living cells and their local *** local topography is one of the key factors regulating cell *** between the surface topography and the cell behaviors is critical to understanding tissue development and *** this study,a dynamic mask photolithography technique has been utilized to fabricate a surface with graded *** has been demonstrated that the cells have been successfully guided to migrate from the sparse zone to the dense *** cell polarization angle has been characterized in both sparse zone and the dense *** to the dense zone,the cells in the sparse zone are more aligned along the direction of the micropillar spacing gradient,which enables the guided cell ***,the effects of the micropillar spacing gradient,micropillar diameter,and micropillar height have been investigated in terms of the cell migration speed and cell spreading ***,two issues significantly affecting the cell migration have been discussed:trapped cells between the micropillars and cell clusters.

摘要：In order to investigate the design method for a micro centrifugal compressor, which is the most important component of an ultra micro gas turbine, two types of centrifugal impeller with 2-dimensional blade were designed, manufactured and tested. These impellers have different shapes of hub on the meridional plane with each other. Moreover, these types of impeller were made for the 5 times and the 6 times size of the final target centrifugal impeller with the outer diameter of 4ram in order to assess the similitude for the impellers. The comparison among the performance characteristics of the impellers revealed the influence of the meridional configuration on the performance and the similitude of the compressors.

摘要：3D solid models for parts with regular-form surfaces (PRFSs) are effectively generated using traditional parametric design techniques. A new model is obtained by changing some parameters defining the model. The parts with free-form surfaces (PFFSs), however, cannot be defined by several parameters. Usually they are defined by some geometric elements like profile curves. The traditional parametric design approaches have not easily dealt with the PFFSs. A method for generating a solid model and an engineering drawing for PFFSs is proposed in this paper: First, the new profiles are generated from input point data. Second, the profile information is extracted from the existing model. Last, the old profiles are replaced with the new profiles. This method can preserve the associative information of the existing model and automatically generate the drawing including views, dimen- sions, and annotations. The proposed method has been implemented using a commercial CAD/CAM system, Unigraphics, and API functions written in C-language, and were applied to the blades of a turbine generator. Some illustrative examples are pro- vided in order to show the effectiveness of the proposed method.

摘要：Biomanufacturing(BM)is a multidisciplinary area incorporating the characteristics of living organisms and engineering principles to create valuable products for various sectors,including medicine,energy,and the *** has undergone a remarkable transformation in the last two decades,entering the era of BM4.0 and becoming a pivotal driver of the sustainable ***,Japan has made significant advances in BM,contributing to its development through the creation of innovative materials,advanced processes,and interdisciplinary ***,because of certain development policies,this research has not been widely recognized on an international *** paper provides a comprehensive summary of the research progress made by renowned Japanese laboratories and researchers in biomedical materials,bio-three-dimensional(3D)printing,and biomedical applications in the last five *** unique contributions are introduced and analyzed,illuminating the distinctive approaches and breakthroughs within each ***,this review highlights the current challenges and prospects of *** viewpoints presented in this paper are intended to serve as a valuable reference for scholars studying BM in Japan.

摘要：In order to monitor deformation of high temperature components for a long time,a sensing device integrating a bridge-shaped mechanical displacement amplifier has been *** sensing device has higher resolution and accuracy than conventional ***,the relation between the magnification ratio and the structure size of the displacement amplifier is a bottleneck of sensing device *** this,the magnification ratio of a mechanical displacement amplifier is analytically derived based on its geometry *** prototypes of the displacement amplifier made in propathene are manufactured,and an experimental system is set up to validate the accuracy of the established magnification ratio *** magnification ratios and experimental magnification ratios are compared and agree well,which verifies that the proposed equation is *** analytical equation provides an effective design method for bridge-shaped mechanical displacement amplifiers with an expected magnification ratio.