摘要：A novel type of chiral molecular tweezers has been designed and synthesized by using deoxycholic acid as backbone and ethanoyl and the chiral unsymmetrical urea unit as arms. Their structures were characterized by 1H NMR, IR, MS spectra and elemental analysis. These molecular tweezers showed good binding ability for neutral molecules and chiral molecules.

摘要：A novel type of molecular tweezer receptors based on deoxycholic acid has been designed and synthesized and their binding properties were examined by UV-vis spectral titration. These molecular tweezers showed a high selectivity toward F^- over Cl^-, Br^-, I^-, AcO^-, H2PO4^-.

摘要：The continuous developing features in the design of mechanical product and based on 3D entity model is aimed at, and the extension of the 4-dimensional model with the process of designing, the knowledge described model on the level of semantic understanding and summarizing the designing process and the way of discovering knowledge from multi-information model are studied. On the basis of designing the broad sensed collaborative system, through discussion of the relationship between the implicit knowledge of the users and the designing knowledge as well as commanding all the designing links, taking advantage of the way of concluding and deducting in the concept of the designers, the synthetic knowledge unit formed in the dynamic process from the conception design t9 the last design is schemed out, and the knowledge discovered principle in the dynamic designing process of the mechanical products and the key technology in its implementation under the milieu of network is brought forward.

摘要：Interior design is unable to attract people＇s attention without a thematic concept. However, it is a systematic project to determine a thematic concept of interior design, which should be fully prepared in advance, but never defined casually. In this paper, this topic is discussed. Therefore, this paper is of certain practical significance and guiding significance.

摘要：A series of chalcone-benzotriazole conjugates as new potential antimicrobial agents were synthesized and char- acterized by ^1H NMR, ^13C NMR, IR and HRMS spectra. Antimicrobial assay manifested that some target com- pounds gave moderate to good antibacterial and antifungal activities. The N- 1 derived benzotriazole 5e and N-2 de- rived benzotriazole 6a exhibited valuable inhibitory efficacy against some tested strains. Especially, derivative 6a gave superior antifungal efficacies against C. utilis, S. cerevisiae and A. flavus （MIC^0.01, 0.02, 0.02 gmol/mL, respectively） to Fluconazole. The drug combination of compound 5e or 6a with antibacterial Chloromycin, Nor- floxacin and antifungal Fluconazole respectively showed stronger antimicrobial efficiency with less dosage and broader antimicrobial spectrum than their separated use alone. The preliminary interaction with calf thymus DNA revealed that compound 6a could intercalate into DNA to form 6a-DNA supramolecular complex which might be a factor to exert its powerful bioactivity. Molecular docking study indicated strong binding of compound 6a with DNA gyrase. The structural parameters such as molecular orbital energy and molecular electrostatic potential of compound 6a were also investigated, which provided better understanding for its good antimicrobial activity.

摘要：Chinese traditional culture is a valuable asset, and we must continue to inherit and carry forward the fine traditional culture of the Chinese nation. This paper discusses the impact of packaging design in aspects of colors, graphics, materials, one by one. Color is the most direct visual language, giving a deep impression. The use of traditional patterns can reflect the national spirit and national culture. People can also generate intimacy, affecting the consumer＇ s desire to purchase. The national characteristic of the goods has a strong aesthetic characteristic, can reflect national pride. Traditional culture input a lot of fresh blood into China＇ s packaging design, with the combination of modem packaging. China＇ s Marriage is formed in a long historical and cultural heritage of the Chinese nation; its source can be traced back several hundred thousand years ago. But the wedding industry rises in recent decades, with the rapid social development of new era, commercial activities have become increasingly frequent, wedding gift packaging design requirements have been increased from the basic material needs to spiritual needs. I think if the wedding gift wrapping design wants to be competitive on the market; it needs to create a new personal design philosophy.

摘要：The importance of urban portal has been improved, but the phenomenon of image convergence has become increasingly prominent. The urban design of urban portal area should analyze and refine the regional culture of landscape culture, life culture, architectural culture, historical culture and so on, and combine with the design contents such as functional orientation, spatial pattern, public space, architectural style and landscape environment.