摘要：In this work,the nickel-based powder metallurgy superalloy FGH95 was selected as experimental material,and the experimental parameters in multiple overlap laser shock processing(LSP)treatment were selected based on orthogonal experimental *** experimental data of residual stress and microhardness were measured in the same *** residual stress and microhardness laws were investigated and *** neural network(ANN)with four layers(4-N-(N-1)-2)was applied to predict the residual stress and microhardness of FGH95 subjected to multiple overlap *** experimental data were divided as training-testing sets in *** energy,overlap rate,shocked times and depth were set as inputs,while residual stress and microhardness were set as *** prediction performances with different network configuration of developed ANN models were compared and *** developed ANN model with network configuration of 4-7-6-2 showed the best predict *** predicted values showed a good agreement with the experimental *** addition,the correlation coefficients among all the parameters and the effect of LSP parameters on materials response were *** can be concluded that ANN is a useful method to predict residual stress and microhardness of material subjected to LSP when with limited experimental data.

摘要：Cu−Fe alloys with different Fe contents were prepared by vacuum hot *** hot rolling and aging treatment,the effects of Fe content on microstructure,mechanical properties and electrical conductivity of Cu−Fe alloys were *** results show that,when w(Fe)<60%,the dynamic recrystallization extent of both Cu phase and Fe phase *** w(Fe)≥60%,Cu phase is uniformly distributed into the Fe phase and the deformation of alloy is more *** the increase of the Fe content,the tensile strength of Cu−5wt.%Fe alloy increases from 305 MPa to 736 MPa of Cu−70wt.%Fe alloy,the elongation decreases from 23%to 17%and the electrical conductivity decreases from 31%IACS to 19%*** results provide a guidance for the composition and processing design of Cu−Fe alloys.

摘要：Catalytic hydrogenation is a vital industrial means to produce value-added fuels and fine chemicals,however, requiring highly efficient catalysts, especially the nonprecious ones. To date, the majority of high-performance industrial hydrogenation catalysts are made of precious metals-based materials, and any given catalyst could only be used to catalyze one or few specific reactions. Herein, we exemplify a crystal phase engineering approach to empower Ni nanoparticles(NPs) with superb intrinsic catalytic activities toward a wide spectrum of hydrogenation reactions. A facile pyrolysis approach is used to directly convert a Ni-imidazole MOF precursor into hexagonal close-packed(hcp)-phased Ni NPs on carbon support. The as-synthesized hcp-phased Ni NPs exhibit unprecedented hydrogenation catalytic activities in pure water towards nitro-, aldehyde-, ketone-, alkene-and N heterocyclic-compounds, outperforming the face-centered cubic(fcc)-Ni counterpart and the reported transition metalsbased catalysts. The density functional theory calculations unveil that the presence of hcp-Ni boosts the intrinsic catalytic hydrogenation activity by coherently enhancing the substrate adsorption strength and lowering the reaction barrier energy of the rate-determining step. We anticipate that the crystal phase engineering design approach unveiled in this work would be adoptable to other types of reactions.

摘要：地点﹕泰国南方的三家研究所,11家医院及38家社区医院。目的:评估泰国南方结核病医疗机构使用的抗结核药物质量及其管理系统。设计﹕利用访视、查阅文件、观察药物储存、检查药物并行异烟肼(IINH)、利福平(RMP)、吡嗪酰胺(PZA)及乙胺丁醇(EMB)样品的实验室分析。结果﹕任何级别单位均未发现有抗结核药物的脱销。13家医院/研究所(25%)撤去了EMB糖衣片的箔包装。11家医院/研究所(21%)将EMB糖衣片一分为二,作为200mg片分发。观察发现,在44%医院/研究所肉眼发现有变质受损的EMB。除了14%的EMB外,全部药物样品均通过了含量测定。INH与EMB均通过了溶解试验评价,但有62%的RMP及26%的PZA样本未通过。结论﹕在结核病控制方面,不达标的变质受损抗结核药物是一个严重问题。研究地区的抗结核药物管理也存在问题。关于抗结核药物包装、储存的培训及建立分发、清单管理,质量保证和督查的完整体系是主要的控制措施。

摘要：Strontium-90,a highly radioactive isotope,accumulates within the food chain and skeletal structure,posing significant risks to human *** is a critical need for a sensitive detection strategy for Strontium-90 in complex environmental ***,solid-state nanochannels,modified with metal-organic frameworks(MOF)and specific aptamers,were engineered for highly sensitive detection of strontium ion(Sr^(2+)).The synergistic effect between the reduced effective diameter of the nanochannels due to MOF and the specific binding of Sr^(2+) by aptamers amplifies the difference in ionic current signals,enhancing detection sensitivity *** MOF-modified nanochannels exhibit highly sensitive detection of Sr^(2+),with a limit of detection(LOD)being 0.03 nmol·L^(-1),whereas the LOD for anodized aluminum oxide(AAO)without the modified MOF nanosheets is only 1000 nmol·L^(-1).These findings indicate that the LOD of Sr^(2+) detected by the MOF-modified nanochannels is approximately 33,000 times higher than that by the nanochannels without MOF ***,the highly reliable detection of Sr^(2+) in various water samples was achieved,with a recovery rate ranging from 94.00%to 118.70%.This study provides valuable insights into the rapidly advancing field of advanced nanochannel-based sensors and their diverse applications for analyzing complex samples,including environmental contaminant detection,food analysis,medical diagnostics,and more.

摘要：Microbial synthesis of carotenoids is a highly desirable alternative to plant extraction and chemical *** this study,we investigated multidimensional strategies to improve the carotenoid synthesis in the industrial workhorse of Saccharomyces ***,we rewired the yeast central metabolism by optimizing non-oxidative glycolysis pathway for an improved acetyl-CoA ***,we restricted the consumption of farnesyl pyrophosphate(FPP)by the down-regulation of squalene synthase using the PEST ***,we further explored the human lipid binding/transfer protein saposin B(hSapB)-mediated metabolic sink for an enhanced storage of lipophilic ***,the copper-induced GAL expression system was engineered to function in the yeast-peptone-dextrose medium for an increased biomass *** combining the abovementioned strategies,the final engineered yeast produced 166.79±10.43 mg/Ⅰβ-carotene in shake flasks,which was nearly 5-fold improvement of the parental carotenoid-producing ***,we envision that multidimensional strategies reported here might be applicable to other hosts for the future industrial development of carotenoid synthesis from renewable feedstocks.

摘要：As an important energy carrier in terms of carbon neutrality,green hydrogen produced by water electrolysis using renewable electricity has attracted worldwide *** polymer electrolyte water electrolyzer(PEWE)has the potential to be a mainstay in the green hydrogen market in the future because of its superior ***,the development of PEWE is constrained by the slow progress of the membrane electrode assembly(MEA),which is an essential component of PEWE and largely determines the cost and performance of the ***,the MEA must be optimized from the aspects of reducing cost and improving performance to promote the development of *** this review,we first discuss the recent progress of the materials and design strategies of MEA,including the cost,activity,and stability of catalysts,distribution and thickness of ionomers,and ion transport efficiency of ion exchange membranes(IEMs).Then,the effects of all components and interlayer interfaces on the ions,electrons,and mass transfer in MEA and,consequently,the performance of PEWE are ***,we propose perspectives on developing MEA by optimizing the catalyst activity and stability of IEM,interface contact between adjacent components,and evaluation methods of performance.

摘要：Polyurethane elastomers with covalent adaptable networks(PU-CANs)based on the dynamic urethane bond have attracted remarkable attention owing to their reprocessability,adaptability,and ***,it is still a formidable challenge to achieve excellent dynamics at low temperatures since the urethane bond energy is usually ***,a fluorinated phenolic polyurethane(FPPU)elastomer with CANs based on phenol±carbamate bonds was successfully designed and ***,the effects of fluorine atoms on the mechanical properties,thermal stability,reprocessability,and self-healability,surface free energy,and hydrophobicity of the prepared elastomers were systematically *** FPPU elastomer showed notch-insensitivity,remarkable self-healable efficiency(98%),low dynamic dissociation temperature(60℃),excellent reprocessability,and low surface energy(62 MJ m^(-2))compared with non-fluorinated counterpart phenolic polyurethane elastomer(APPU).Based on the above-mentioned features,FPPU was selected as an elastic substrate to assemble into a triboelectric nanogenerator(TENG)to harvest energy from natural *** TENG exhibited an excellent electrical output performance with a peak open-circuit voltage of 103 V,a peak short-circuit current of 4.7μA and a peak short-circuit charge of 43 *** addition,the TENG possessed high selfcleaning and reprocessing ***,a stretchable and self-healing composite conductor based on FPPU was fabricated for flexible electronic devices.