摘要：iot(1924)was a remarkable artistic *** collages in the works of Picasso,Braque,and Gris,publisher Bill Bird created a collage of newspaper headlines on the cover of that slim volume that linked to the collage of vignettes within that Hemingway *** depicted a world losing traditional values,torn by war and despair and increasing *** Hemingway book covers by Scribners,at least until The Old Man and the Sea,emphasized sales over art and had little to do with content.

摘要：女性患者，64岁，因慢性膝关节退行性病变伴疼痛在全身麻醉下行全膝关节成形术（TKA），既往有哮喘和高血压病史。按照研究设计，手术中采用经食道超声（TEE）对手术引发的栓子进行定量监测。

摘要：基于监控数据及车辆总线数据的营运车驾驶行为评价研究方法已相对成熟,但难以推广至私家车,针对自然驾驶试验样本容量小、设备昂贵的缺点,提出了一种基于海量秒级GPS导航数据的驾驶行为评价方法.运用自动编码机对数据进行降噪处理,结合行车动力学、SOM自组织映射分类等方法给出超速、急变速、频繁变道、急转弯等行为的判定方法及阈值,计算不同驾驶特性驾驶员及危险驾驶行为比例.在此基础上,分析得到深圳市机动车驾驶员驾驶行为时空分布特征、典型通道驾驶行为特征,并选取典型道路进行事故多发段与正常段的驾驶行为对比.结果表明,深圳危险驾驶行为以频繁变道和超速为主,16.1%的驾驶员驾驶行为偏冒进,原特区外相对原特区内危险驾驶行为比例更高,危险驾驶行为与事故密度呈高度相关.

摘要：采用激光动态光散射测量技术 ,通过 (氢气十铬 ) /空气扩散火焰研究了含铬废物燃烧过程中Cr2 O3 的气溶胶颗粒尺寸。通过求解轴对称形式的Navier -Stokes方程 ,计算出流场、温度场和组分 (包括颗粒 )浓度 ,采用离散分区模型对Cr2 O3 气溶胶颗粒进行了数值模拟。

摘要：Global demand for food and bioenergy production has increased rapidly,while the area of arable land has been declining for decades due to damage caused by erosion,pollution,sea level rise,urban development,soil salinization,and water scarcity driven by global climate *** order to overcome this conflict,there is an urgent need to adapt conventional agriculture to water-limited and hotter conditions with plant crop systems that display higher water-use efficiency(WUE).Crassulacean acid metabolism(CAM)species have substantially higher WUE than species performing C3 or C4 *** plants are derived from C3 photosynthesis ***,it is extremely unlikely that the C3 or C4 crop plants would evolve rapidly into CAM photosynthesis without human ***,there is growing interest in improving WUE through transferring CAM into C3 ***,engineering a major metabolic plant pathway,like CAM,is challenging and requires a comprehensive deep understanding of the enzymatic reactions and regulatory networks in both C3 and CAM photosynthesis,as well as overcoming physiometabolic limitations such as diurnal stomatal *** advances in CAM evolutionary genomics research,genome editing,and synthetic biology have increased the likelihood of successful acceleration of C3-to-CAM ***,we first summarize the systems biology-level understanding of the molecular processes in the CAM ***,we review the principles of CAM engineering in an evolutionary ***,we discuss the technical approaches to accelerate the C3-to-CAM transition in plants using synthetic biology toolboxes.

摘要：Human life intimately depends on plants for food,biomaterials,health,energy,and a sustainable *** plants have been genetically improved mostly through breeding,along with limited modification via genetic engineering,yet they are still not able to meet the ever-increasing needs,in terms of both quantity and quality,resulting from the rapid increase in world population and expected standards of living.A step change that may address these challenges would be to expand the potential of plants using biosystems design *** represents a shift in plant science research from relatively simple trial-and-error approaches to innovative strategies based on predictive models of biological *** biosystems design seeks to accelerate plant genetic improvement using genome editing and genetic circuit engineering or create novel plant systems through de novo synthesis of plant *** this perspective,we present a comprehensive roadmap of plant biosystems design covering theories,principles,and technical methods,along with potential applications in basic and applied plant biology *** highlight current challenges,future opportunities,and research priorities,along with a framework for international collaboration,towards rapid advancement of this emerging interdisciplinary area of ***,we discuss the importance of social responsibility in utilizing plant biosystems design and suggest strategies for improving public perception,trust,and acceptance.

摘要：目的 通过计算绝经后妇女一生中主动吸烟和被动吸烟的量来评估吸烟与浸润性乳腺癌发病风险的关系。 设计 前瞻性队列研究。 单位 美国的40个医疗中心。 研究对象 79 990名年龄50～79岁，在1993－1998年间参加了女性健康初步随访研究的绝经后妇女。 主要终点 自我测定主动吸烟和被动吸烟的数量，有病理学证实的浸润性乳腺癌。 结果 平均随访10.3年后，共有3520人被确诊为浸润性乳腺癌。与从不吸烟的妇女相比，既往吸烟者罹患乳腺癌的风险高出9%(风险比1.09，95%可信区间1.02～1.17)，而仍在吸烟的妇女患病风险则高出16%(风险比1.16，95%可信区间1.00～1.34)。主动吸烟的时间长和吸烟量大的妇女乳腺癌患病率显著升高，从青少年时期就开始吸烟的女性更是如此。结果发现吸烟≥50年的女性乳腺癌发病风险最高(与从不吸烟者相比，风险比为1.35，95%可信区间1.03～1.77)；与从不吸烟且无被动吸烟者相比，风险比为1.45，95%可信区间1.06～1.98。吸烟导致的乳腺癌发病风险增高可以持续至戒烟后的20年。在从未吸过烟的女性中，矫正了潜在混杂因素后，那些长期被动吸烟(儿童时期≥10年，成年后在家中被动吸烟≥20年或者在工作中被动吸烟≥10年)的妇女乳腺癌发病风险比那些没有被动吸烟史的妇女高32%(风险比1.32，1.04～1.67)。然而，在其他暴露量较低的组中没有发现被动吸烟与乳腺发病率有明显联系，发病风险和被动吸烟量的累积也没有明确的量效关系。 结论 主动吸烟与绝经期妇女的乳腺癌发病风险增高相关。被动吸烟也有可能与乳腺癌发病风险增高有关。