摘要：Ensuring a sufficient oxygen supply is pivotal for the success of bioprinting applications since it fosters tissue integration and natural *** in oxygen concentration among diverse tissues necessitates the precise recreation of tissue-specific oxygen levels in imprinted constructs to support the survival of targeted *** oxygen-releasing biomaterials,such as oxygen-generating microparticles(OMPs),have shown promise for enhancing the oxygen supply of microenvironments in injured tissues,whether this approach is scalable for large tissues and whether tissue-specific bioinks with varying OMP concentrations remain printable remain *** study addresses this critical gap by introducing an innovative class of engineered oxygenated bioinks that combine colloidal-based microgels with *** report that incorporating nanosized calcium peroxide(nCaO_(2))and manganese oxide nanosheets(nMnO_(2))into hydrophobic polymeric microparticles enables precise modulation of oxygen release while controlling hydrogen peroxide ***,the fabrication of oxygenating and cytocompatible colloidal gels is achieved using an aqueous two-phase *** study thoroughly evaluates the fundamental characteristics of the resulting bioink,including its rheological behaviors,printability,shape fidelity,mechanical properties,and oxygen release ***,this study demonstrates the macroscopic scalability and cytocompatibility of printed constructs produced via cell-laden oxygenating colloidal *** showcasing the effectiveness of extrusion-based bioprinting,this study underscores how it can be used to fabricate biomimetic tissues,indicating its potential for new *** findings presented here advance the bioprinting field by achieving scalability with both high cell viability and the possibility of mimicking specifically oxygenated *** work thereby offers a promising avenue for the development of functional tissues with e

摘要：感应淬火冷却系统可能采用各式各样的搅拌方式,包括传统的浸淬、开放式喷雾冷却和浸没状态下的喷射冷却。这些工艺并不等效,而是要根据正确的技术要求来恰当地选用这些方法。本文对这些不同的搅拌系统进行了综述。

摘要：Hazard prevention in mission plans requires careful analysis and appropriate tools to support the design of preventive and/or corrective *** is most challenging in systems with large sets of states and complex state *** the case of sociotechnical systems,hazard prevention becomes even more dicult given that the behaviour of human centric components can at best be partially *** the present article we focus on a specic class of sociotechnical systems-namely air spaces containing pilot controlled as well as autonomous aircrafts and introduce the notion of relevant *** also introduce soft institutions as an appropriate basis for analysis,with the aim of addressing relevant *** concept of soft institutions is drawn from specication languages for interaction between agents in multi-agent systems but,in our case,is adapted for use in systems that combine human and automated actors.

摘要：Critical bone defects are considered one of the major clinical challenges in reconstructive bone *** combination of 3D printed conductive scaffolds and exogenous electrical stimulation(ES)is a potential favorable approach for bone tissue *** this study,3D conductive scaffolds made with biocompatible and biodegradable polycaprolactone(PCL)and multi-walled carbon nanotubes(MWCNTs)were produced using the extrusion-based additive manufacturing to treat large calvary bone defects in *** results show that the use of PCL/MWCNTs scaffolds and ES contributes to thicker and increased bone tissue formation within the bone *** and mineralization are also significantly promoted using high concentration of MWCNTs(3 wt%)and ***,scaffolds favor the tartrate-resistant acid phosphatase(TRAP)positive cell formation,while the addition of MWCNTs seems to inhibit the osteoclastogenesis but present limited effects on the osteoclast functionalities(receptor activator of nuclear factor κβ ligand(RANKL)and osteoprotegerin(OPG)expressions).The use of ES promotes the osteoclastogenesis and RANKL expressions,showing a dominant effect in the bone remodeling *** results indicate that the combination of 3D printed conductive PCL/MWCNTs scaffold and ES is a promising strategy to treat critical bone defects and provide a cue to establish an optimal protocol to use conductive scaffolds and ES for bone tissue engineering.

摘要：We used existing studies on the integration of user experience design and agile methods as a basis to develop a framework for integrating UX and Agile. We performed a field study in an ongoing project of a medium-sized company in order to check if the proposed framework fits in the real world, and how some aspects of the integration of UX and Agile work in a real project. This led us to some conclusions situating contributions from practice to theory and back again. The framework is briefly described in this paper and consists of a set of practices, artifacts, and techniques derived from the literature. By combining theory and practice we were able to confirm some thoughts and identify some gaps—both in the company process and in our proposed framework—and drive our attention to new issues that need to be addressed. We believe that the most important issues in our case study are: UX designers cannot collaborate closely with developers because UX designers are working on multiple projects and that UX designers cannot work up front because they are too busy with too many projects at the same time.

摘要：在超精密设计中,很可能没有可供选择的设计方案。在超精细进给情况下,压电执行器是一种潜在选择。目前,欧洲和日本刀具制造商为此正致力于磁致伸缩执行器的研究。压电材料和磁致伸缩材料都存在磁滞型非线性,以致这些系统的输出依赖于以前的输入,绝对定位仅通过反馈控制才能得到。本文采用模拟技术对脆性材料的超精密加工中(微米级)刀架定位的几种现代控制技术作了一番比较。

摘要：The main focus of this paper is the analysis on how social business recent management proposals fit to a media/journalistic business environment. The discussion was based on three research questions focusing on: the drivers and the constraints of disruption innovation strategies; the adequate social business design framework to promote innovation; and an evaluation over the practices/experiences related to disruption, innovation, and creativity in journalistic businesses. A conceptual framework the Latour/Law Actor-Network Theory (ANT) has been taken as. Six possible dimensions of action to make this framework valuable some successful practices have also been identified, and in this paper the authors view over these concepts. The main conclusion goes through the understanding of journalistic culture and legitimacy embedded for centuries over society, and to change this will depend on multiple enablers.