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Design,synthesis and biological activity of some novel benzimidazole derivatives against Coxsackie virus B_3: 收藏
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引用; 《Chinese Chemical Letters》2009年第8期20卷 921-923页; 作者：Zhong Lv Zhang Zhi Jie Sun Fei Xue Xian Jin Luo Nai Yun Xiu Li Teng Zong Gen PengSchool of Chemistry and Chemical Engineering Shanghai Jiaotong University Shanghai 200240 PR China School of Life Science and Environmental Science Shanghai Normal University Shanghai 200234 PR China cInstitute of Medicinal Biotechnology Chinese Academy of Medical Science and Peking Union Medical College Beijing 100050 PR China; A series of novel benzimidazole derivatives was synthesized and their anti-Coxsackie virus B3 （CVB3） activity was evaluated in VERO ceils. Compounds 9 and 10 exhibited better inhibitory activity than those of ribavi...; A series of novel benzimidazole derivatives was synthesized and their anti-Coxsackie virus B3 （CVB3） activity was evaluated in VERO ceils. Compounds 9 and 10 exhibited better inhibitory activity than those of ribavirin （RBV） with IC50 values of 5.30 and 1.06 μg/mL, respectively. ？2009 Xian Jin Luo. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.; 来源：详细信息评论

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